LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH
نویسندگان
چکیده
منابع مشابه
LECT2 functions as a hepatokine that links obesity to skeletal muscle insulin resistance.
Recent articles have reported an association between fatty liver disease and systemic insulin resistance in humans, but the causal relationship remains unclear. The liver may contribute to muscle insulin resistance by releasing secretory proteins called hepatokines. Here we demonstrate that leukocyte cell-derived chemotaxin 2 (LECT2), an energy-sensing hepatokine, is a link between obesity and ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-020-80689-0